TABLE 3.

In vivo-expressed gene candidates discovered by IVIAT in V. vulnificus

Putative protein function and identified cloneHomologous protein in database (organism [% identity])
Signaling
    Vv-Ive-1MCP VC0906 (V. cholerae [30])
    Vv-Ive-2GGDEF-containing protein STM3388 (S. enterica serovar Typhimurium LT2 [32])
    Vv-Ive-3Putative serine/threonine protein kinase STM2520 (S. enterica serovar Typhimurium LT2 [45])
Biosynthesis and metabolism
    Vv-Ive-4Uridylate kinase (UMP kinase) PyrH VC2258 (V. cholerae [77])
    Vv-Ive-5AICAR transformylase/IMP cyclooxygenase PurH VC0276 (V. cholerae [92])
    Vv-Ive-6Putative acetohydroxyacid isomeroreductase IlvC VC0162 (V. cholerae [80])
Secretion
    Vv-Ive-7Sec-independent protein translocase TatB VC0087 (V. cholerae [76])
    Vv-Ive-8PAS factor, a protein secretion factor (V. alginolyticus [85])
Transcriptional activator
    Vv-Ive-9LysR-type transcriptional regulator IlvY VC0161 (V. cholerae [43])
    Vv-Ive-10Transcriptional activator HlyU VC0678 (V. cholerae [64])
Known hypothetical protein
    Vv-Ive-11Putative lipoprotein gene YaeC VC0905 (V. cholerae [74])
    Vv-Ive-12Conserved hypothetical protein VC1606 (V. cholerae [56])