TABLE 1.

Maternal anti-SAG1 IgG1 and IgG2a antibody titers on day 19 of gestation (day 7 of infection)

MiceImmunization regimenAnti-SAG1 antibody titera
IgG1IgG2a
BALB/cVehicle (control)<1/25<1/25
<1/25<1/25
<1/25<1/25
<1/25<1/25
SAG11/20,0001/100
1/40,0001/100
1/40,0001/50
1/80,0001/200
1/40,0001/100
1/40,0001/100
CBA/JVehicle (control)<1/25<1/25
<1/25<1/25
<1/25<1/25
SAG11/500<1/25
1/500<1/25
1/500<1/25
1/1,000<1/25
  • a IgG titers are expressed as the last dilution giving an absorbance value twice that of the mean absorbance of three negative controls.