TABLE 1

Homology of predicted proteins of strain 81-176 to other C. jejuni proteins

Strain 81-176Strain (protein)b% Identity, % similaritycPredicted protein
ORFPredicted molecular mass (kDa)aGene
134.6 (291) cstlI 4344695, 95 (291)Sialyltransferase
OH438492, 93 (291)
11168 (Cj1140)52, 66 (289)
238.1 (346) neuB1 OH438495, 95 (346)Sialic acid synthase
4344694, 94 (346)
11168 (Cj1141)74, 85 (343)
340.5 (354) neuC1 4344698, 98 (352)Mannosamine synthesis
OH438498, 98 (352)
11168 (Cj1142)69, 84 (352)
437.4 (315) cgtA 11168 (Cj1143)65, 80 (308) N-Acetylgalactosaminyltransferase
OH438447, 64 (292)
525.0 (221) neuA OH438484, 85 (221)CMP-NeuNAc synthetase
11168 (Cj1143)61, 72 (218)
  • a Numbers in parentheses indicate the predicted numbers of amino acid residues.

  • b Strains 43446 and OH4384 were described by Gilbert et al. (11), and strain 11168 has been described by Parkhill et al. (27). Gene product Cj1143 of NCTC 11168 was identified as a CMP-NeuNAc synthetase (27), but the ORF appears to encode a fusion protein in that strain and in MSC57360 (12). Mutational analysis of this gene in MSC57360 showed that the predicted protein functioned as a GalNAc transferase (12). In 81-176, there are two distinct ORFs that correspond to the amino (ORF4) and carboxy (ORF5) ends of the Cj1143 protein.

  • c Numbers in parentheses indicate actual total numbers of amino acid residues in each protein.