TABLE 6.

Effect of parenteral challenge of B. mallei-vaccinated BALB/c mice

GroupImmunogenaNo. of miceChallengebNo. of survivorsc
B. mallei strainNo. of cells
IHKGB155GB15.1-22.3 × 1080
IRGB154GB15.1-22.3 × 1081
CapGB155GB15.1-22.3 × 1080
IIIRGB155GB15.1-22.8 × 1081
IRGB155CapGB152.8 × 1085
IRGB155CapGB156.5 × 1084
Adjuvant5GB15.1-22.8 × 1080
  • a Two vaccinations were given per mouse as stated in Materials and Methods.

  • b Mice were challenged i.p. 3 to 4 weeks after the second vaccination.

  • c Mice were observed for 21 days after the challenge.