TABLE 4.

Crypt heights and colon weights of mice 14 days after infection with derivatives of C. rodentium

StrainCrypt ht (μm)aColon wtb (mg/cm)
ICC169301 ± 63c30.6 ± 3.4c
ICA15189 ± 1123.4 ± 1.7
ICA15(pAC4)250 ± 15cND
ICA18260 ± 21c34.8 ± 4.5c
None (PBS control)199 ± 1824.1 ± 2.0
  • a Only well-oriented crypts taken from the distal colon of each mouse were measured. Data are the means ± SD of the results (n = 10).

  • b Colon weight after removal of contents. Data are the means ± SD of the results (n = 5). ND, not determined.

  • c Significantly different (P < 0.01) from results for control mice inoculated with PBS (Student's t test, two-tailed).