TABLE 3.

Association between Lewis blood group phenotypes of the BC children and symptomatic and asymptomatic infections with ETEC expressing different CFs

CF (toxin ratio) expressed by ETECType of ETEC infectionNo. (%) of children with indicated phenotypePb
Le(a+b−) (n = 41)aLe(a−b+) (n = 102)
CFA/I (LT:ST:LT/ST = 0:36:5)Symptomatic7 (17)6 (6)0.075
Asymptomatic9 (22)19 (19)NS
CFA/I group fimbriae (CFA/I, CS14, and CS17) (LT:ST:LT/ST = 8:55:10)Symptomatic11 (27)11 (11)0.032
Asymptomatic13 (32)38 (37)NS
CFA/I group including strains co-expressing CS3 (CFA/I, CS14, CS17, CS1+CS3, and CS2+CS3) (LT:ST:LT/ST = 10:69:18)Symptomatic18 (44)16 (16)<0.001
Asymptomatic16 (40)47 (46)NS
CFA/II group (CS3 only, CS1+CS3, and CS2+CS3) (LT:ST:LT/ST = 2:15:12)Symptomatic10 (24)5 (5)0.002
Asymptomatic5 (12)9 (9)NS
CS6 (CS6 only and CS5+CS6 strains) (LT:ST:LT/ST = 3:38:18)Symptomatic8 (20)17 (17)NS
Asymptomatic9 (22)25 (25)NS
  • a A total of 143/179 children with Le(a−b+) and Le(a+b−) blood groups had an ETEC infection; we excluded 24 Le(a−b−) and 12 non-ETEC-infected children from this analysis.

  • b Statistical analysis was done for the relationship between children with the Le(a−b+) phenotype and children with the Le(a+b−) phenotype. NS, not statistically significant.