TABLE 3.

List of E. coli genes identified to be in vivo induced

ClassGene or ORFMap positionProduct or function
Amino acid metabolism dadX 26.688Alanine racemase
aroA 20.651Chorismate biosynthesis
argD 75.155Acetylomithine aminotransferase
metK 66.492 S-Adenosylmethionine synthetase
RNA and protein biosynthesis, degradation, and modification me 24.582mRNA turnover, maturation of 5S RNA
rrsB 89.76216S rRNA
tufB 89.962Elongation factor Tu
fdhA 80.994Selenocysteine synthesis
msrA 95.687Peptide methionine sulfoxide reductase
hslV 88.794Heat shock protein VU, proteasome-related peptidease subunit
clpA 19.885ATP-binding component of serine protease
prpB 7.499Phosphoprotein phosphatase
DNA replication, repair, restriction, and modification dinD 82.242DNA damage-inducible protein
dinG 17.940Probably ATP-dependent helicase
parE 68.363DNA topoisomerase IV subunit B
uvrD 86.126DNA-dependent ATPase I and helicase II
uvrB 17.519DNA repair; excision nuclease subunit B.
dnaA 83.634DNA biosynthesis, initiation of chromosome replication, can be transcription regulator
recG 82.403DNA helicase, resolution of Holliday junction, branch migration
IS91197.134New member of the IS3 group of insertion sequences
trs5 5.891Transposon-related function
Cell division ftsX 77.570Cell division membrane protein
Carbohydrate metabolism pgm 15.364Phosphoglucomutase
bgl 83.8β-Glucoside metabolism
malQ 76.427Maltose degrading enzyme/amylomaltase
Surface structure csgA 23.79Fibronectin and Congo red binding curli pili of E. coli
Peptidoglycan biosynthesis and metabolizing enzymes slt 99.764Soluble lytic murein transglycosylase
bacA 68.998Bactracin resistance, possibly phosphorylates undecaprenol
Transport system ugpB 77.354 sn-Glycerol 3-phosphate transport system, periplasmic binding protein
fepE 13.310Ferric enterobactin (enterochelin) transport
iucA Aerobactin biosynthesis
dcuA 94.047Membrane transport of aspartase
trkH 86.884Potassium uptake.
gltS 82.451Sodium/glutamate symport carrier protein
Outer membrane proteins nlpA 82.704Lipoprotein-28
pldA 86.275Outer membrane phospholipase A
Anaerobic respiration narW 33.08Appears to be essintial for nitrate reductase activity, probably by promoting the correct association of the alpha and beta subunits
hybE 67.648Energy metabolism, carbon: anaerobic respiration.
Drug or analog sensitivity Macromolecule biosynthesis and degradation tehA 32.303Tellurite resistance
menG 88.731Menaquinone biosynthesis protein
menA 88.743Menaquinone biosynthesis protein
birA 89.9Biotin-[acetyl-coenzyme A-carboxylase] ligase
fadB 86.79Fatty acid oxidation pathway
tesB 10.207Fatty acid and phosphatidic acid biosynthesis
gloA 37.202Methylglyoxal metabolism
pntB 36.062Beta subunit of pyridine nucleotide transhydrogenase
appA 22.414Phosphoanhydride phosphorylase
mog 0.200Required for efficient incorporation of molybdate into molybdoproteins
udk 46.136Uridine kinase
Energy metabolism aceE 2.651Pyruvate dehydrogenase
glxB2 11.575Glyoxylate-induced protein
acn 28.752Aconitate hydratase
Cellular repressor of the SOS response dinR Cellular repressor of the SOS response in Bacillus subtilis
Unclassified yejF 49.024Putative ATP-binding component of a transport system
yehU 47.658Putative 2 component sensor protein
hslU 88.765Putative heat shock protein HslVU, ATPase-subunit, homologous to chaperones
yihK 87.428Putative GTP-binding factor
b1284 28.919Putative DEOR-type transcriptional regulator
o169 9.57Putative regulator of flagellar biosynthesis, transcription initiation factor?
o808 35.70Putative oxidoreductase
f344 39.40Putative DNA helicase II
o196 95.651Putative transport protein
o275 8.32Probable ABC transporter permease protein
f278 21.41Probable ABC transporter permease protein
o251 41.83Hypothetical ABC transporter
o127 90.77Putative arginine biosynthesis
f216 23.749Putative regulator
hycF 61.265Probable iron-sulfur protein of hydrogenase 3
b1806 40.7Putative outer membrane protein
yhjE 79.16Putative transport protein
f290 87.667Putative aldose-1-epimerase
Unknown function ygaF 60.095Hypothetical protein
pfs 3.846Hypothetical protein
yddE 33.912Hypothetical protein
yfhH 58.123Hypothetical protein
ycaJ 20.202Hypothetical protein encoded in serS 5′ region
f178 38.94Hypothetical protein
375 87.043Hypothetical RNA methyltransferase
o425 87.551Hypothetical protein
ycjF 29.823Hypothetical protein
o423 78.000Hypothetical protein
b2434 54.96Hypothetical protein
b2362 53.3Hypothetical protein
b1839 41.4Hypothetical protein
o416 85.66Hypothetical protein encoded in rffE-rffT intergenic region