Number of mice that were ear culture positive during the 4-week time course after B. burgdorferi infectiona

Mouse strainNo. of ear punch-positive mice/total no. of mice tested at:
Wk 1Wk 2Wk 3Wk 4
MMP-9 KO0/74/77/77/7
  • a Ear punches were obtained at 1-week intervals, cultured in BSK media, and spotted on a slide for scoring by dark-field microscopy. Five random fields of view were examined for the presence of spirochetes in the culture.