TABLE 4.

Vκ A23 Fab family: H chainsa

FabSequence of H chainJHIsotype
CDR1CDR2CDR3
VH3-23SYAMSAIS*GSGGSTYYADSVKG
    008.1F9-HT-TSLN*EP-DV-R-------VHGSAYJH4IgG1
    008.3C12NNT-TS-N*E--DR-H-------VHGSAHJH1IgG2
    008.3D7DNT-TS-I*DGD-PP--------VHGVPDJH6IgG2
    008.4B12INT-SS--*E--DR-R-------VHGSAHJH1IgG2
    008.2E7-HT-TS-N*EN-DT-H-------VHGDAYJH4IgG2
    025.1C6-D---G--*---TI-------R-STYJH5IgA2
    025.4E12-D---G--*---TI-------R-STFJH5IgA2
    025.7F5ND---G-G*---DV---------STFJH5IgA2
    027.064A-T-TS-GD-G--K---------VHGVPVJH5IgG2
    027.242R-T-TS-V*D-NNRP--------VHGEAYJH5IgA2
    027.304R-T-TS-V*DGNNRP--------VHGEAYJH5IgA1
    027.343R-T-TS-V*NGNNRP--------VHGEPSJH5IgA2
VH3-7SYWMSNIK*QDGSEKYYVDSVKG
    018.6G5-S--G---*H----QS-------DWYRTFDYJH4IgG2
  • a See Table 3, footnote a.