TABLE 6.

Vκ L6 Fab family: H chainsa

FabSequence of H chainJHIsotype
CDR1CDR2CDR3
VH3-30SYGMHVISYDGSNKYYADSVKG
    014.7A2-F-V--V-AG-TTT-------DEGSGSKWCFDYJH4IgG2
    023.102R-----V-S--RTT--------EGGDNKFSFDYJH4IgG2
    025.1H10N-----V-SH-NT---------EGHGSDMTWRADFDYJH4IgG2
    025.5D3N-----LGA--TTT--------EGHASGMTWRADFDYJH4IgA1
    025.7A6H-----V-SG-ET---------EGHSSGMTWRADFDYJH4IgA2
VH3-64SYAMHAISSNGGSTYYADSVKG
    002.7F3G-S----N---D-----V----DIYDVSSAYYGMDVJH6IgG2
VH3-48SYSMNYISSSSSTIYYADSVKG
    008.3A2T--A----GD-G----------SK QQVSGGFYWYFDLJH2IgA2
    008.4A3-N-V-----T-DI---------SRGQQSPLGFYWYFDLJH2IgG2
    008.4D1-N-V----NTG-I----N----SKQQQSTAGFYWYFDLJH2IgG2
    008.2F7TN-V-----T-TI---------SKAQQATAGFYWYFDLJH2IgG2
VH3-23SYAMSAISGSGGSTYYADSVKG
    014.6G9N----SVF--ADN-H-------VLSPGGSNMVWDYJH4IgA1
    014.2B6N----SVF--ADN-H-------VLSPGGSNMVWDYJH4IgG2
  • a See Table 5, footnote a.