TABLE 1.

Phenotype characterization of CD3+ VL after three rounds of infection with C.albicansa

Phenotype% Expression in vaginal T cells from:
Uninfected estrogenized ratsInfected rats
CD3+ αβ+71 ± 1.381 ± 1.3
CD3+ γδ+29 ± 1.219 ± 2.0
CD4+ CD839 ± 1.251 ± 1.5
CD8+ CD461 ± 1.345 ± 2.2
CD4+ αβ+18 ± 1.0b41 ± 1.7b
CD8+ αβ+53 ± 1.3b38 ± 0.7b
CD4+ γδ+17 ± 1.111 ± 0.8
CD8+ γδ+12 ± 0.910 ± 1.5
  • a Measured after pooling the VL of 10 rats in each category. The average ratio of CD4+ to CD8+ T cells in the blood of nonestrogenized, noninfected rats was 3 (more or less 10% variation) (13). Both groups of rats were under similar estrogen treatments.

  • b Fraction of CD4+ (or CD8+) T cells with the indicated TCR phenotype out of all CD3+ T cells with that phenotype.