TABLE 7.

GMTs and 95% CIs of antibody responses to diphtheria toxin in school entry and school leaver children according to vaccine and schedule

GroupVaccineChildrenaPre-DT or Td1 mo post-DT or Td
No.GMT (95% CI)No.GMT (95% CI)
1 (DT or Td, then MCC)Chiron MCC-CRMSENAbNA9214.1 (11.5-17.3)
SLNANA1074.3 (3.6-5.1)
Wyeth MCC-CRMSENANA5812.4 (9.3-16.4)
SLNANA764.7 (4.0-5.5)
Baxter MCC-TTSENANA8712.3 (9.6-15.7)
SLNANA1124.5 (3.8-5.5)
2 (MCC, then DT or Td)Chiron MCC-CRMSE787.1 (15.4-9.2)7815.2 (12.1-19.1)
SL999.4 (7.2-12.3)9910.9 (8.7-13.7)
Wyeth MCC-CRMSE615.4 (3.6-8.2)6112.4 (9.5-16.3)
SL9613.5 (10.0-18.2)9615.4 (12.4-19.1)
Baxter MCC-TTSE780.08 (0.07-0.10)789.7 (7.4-12.8)
SL1000.43 (0.33-0.56)1004.4 (3.5-2.7)
3 (MCC with DT or Td)Chiron MCC-CRMSE920.07 (0.05-0.09)9215.3 (12.6-18.5)
SL1040.20 (0.16-0.25)10410.4 (9.4-13.8)
Wyeth MCC-CRMSE650.06 (0.04-0.08)6515.0 (12.1-18.7)
SL990.21 (0.17-0.27)9918.7 (15.1-23.2)
Baxter MCC-TTSE930.06 (0.05-0.08)9310.4 (8.0-13.6)
SL1000.36 (0.27-0.46)1004.3 (3.8-5.0)
  • a SE, school entry cohort; SL, school leaver cohort.

  • b NA, sample not available.