TABLE 1.

Serum antibody titers of immunized mice the day before challenge with the C. trachomatis MoPn strain

AntigenAdjuvantImmunizationNeutralizing titerAnti-C. trachomatis MoPn ELISA titera
RouteNo. of timesIgMIgAIgGIgG1IgG2aIgG2bIgG3
MOMPCpG + alumi.m. + s.c.1450<10080051,20025,60025,60012,800200
OvalbuminCpG + alumi.m. + s.c.10<100<100<100<100<100<100<100
MOMPCpG + alumi.m. + s.c.3450<1001,600102,40025,60025,6001,600400
OvalbuminCpG + alumi.m. + s.c.30<100<100<100<100<100<100<100
C. trachomatis MoPni.n.11,250<1003,20025,6003,20025,60012,8003,200
  • a ELISA, enzyme-linked immunosorbent assay.