TABLE 3.

In vitro motility of H. pylori tlpA, tlpC, and cheY mutantsa

StrainSwim rate (mm/day)
SS14.5 ± 0.3
SS1 ΔtlpA::cat-24.1 ± 0.8
SS1 ΔtlpC::cat-14.1 ± 0.1
SS1 cheY::aphA3-10.4 ± 0.1
G275.2 ± 0.3
G27 ΔtlpA::cat-15.1 ± 0.9
G27 ΔtlpA::cat-25.0 ± 0.7
G27 ΔtlpC::cat-14.7 ± 0.4
G27 cheY::aphA3-10.75 ± 0.15
  • a Colonial expansion (swim) rates were determined by measuring the colony diameter each day for 7 days of cells grown in brucella broth, 2.5 to 5% fetal bovine serum, and 0.35% agar.