TABLE 1.

Frequency of IFN-γ-producing cells responding to rTB10.4 and TB10.4 peptide mix in comparison to PPD as determined by ELISPOT on two PPD-positive BCG-vaccinated donorsa

AntigenDonor 1Donor 2
IFN-γ concn (pg/ml)Spots/105 cellsIFN-γ concn (pg/ml)Spots/105 cells
PPD113,0008718,00014
rTB10.451,000397,0005
TB10.4 mix41,000326,0005
  • a No antigen is included as a negative control. Antigens were tested in concentrations of 10 μg/ml.