TABLE 2.

Response of CD8+ T cells to stimulation with serovar Typhi Ty21aa

VolunteerT-cell proliferation (cpm)IFN-γ production (pg/ml)
PrebFold increasecPreFold-increase
3801.7<1003.6
42704.3<10015
61301.5<1009.2
5550353,02013
7230374,9600.65
86402812,1001.5
  • a Peripheral blood CD8+ T cells and APC were stimulated with 107 heat-killed serovar Typhi Ty21a bacteria/ml.

  • b Pre, results from samples taken before vaccination.

  • c Results from the peak time points (7 to 21 days after the onset of vaccination) were divided by the prevaccination results.