TABLE 1.

Multivariate logistic regression analysis of variables prior to or in the first 8 weeks of infection compared to results from clinical outcomesa (active disease and latent infection)

VariableInfection typeOdds ratio (95% CI)P value
ActiveLatent
Age (yr)7.88 ± 1.778.22 ± 1.391.05 (0.69-1.62)0.80
GA (% positive)57.116.210.81 (2.09-55.96)0.005
ESR (mm)5.19 ± 8.812.22 ± 4.881.09 (0.90-1.32)0.39
Weight (kg)6.72 ± 1.467.15 ± 1.630.79 (0.49-1.25)0.31
LPA (fold increase from baseline)10.15 ± 10.8817.76 ± 39.60.99 (0.97-1.02)0.75
Gender (male:female)33:431:60.39 (0.039-3.78)0.42
TST (score)3.94 ± 0.763.66 ± 0.711.09 (0.89-1.33)0.39
  • a Age and weight were measured at the time of infection; GA indicates the GA for M. tuberculosis growth in the first 60 days of infection; ESR indicates the peak ESR in the first 60 days of infection; LPA indicates the lymphocyte proliferation assay of PBMC in response to CFP at 6 weeks postinfection compared to values from the preinfection LPA; and TST indicates the peak TST score in the first 60 days of infection (scoring range, 0 to 5). CI, confidence interval.