TABLE 1.

Total genital tract immunoglobulin levels from uninfected and infected volunteers

Sample type and antibody classMedian Ig levels (μg/ml) (range [n])
No previous historyCurrent Infection
Cervical mucus
    IgG15.6 (0.1-178.6 [14])6.1 (0.3-89.8 [11])
    IgM0.3 (0.0-64.0 [14])4.6 (0.1-34.5 [11])
    IgA9.6 (0.2-121.5 [14])8 (0.0-88.5 [11])
Seminal plasma
    IgG75.7 (49.5-187.0 [4])75.5 (34.6-727.5 [9])
    IgM1.2 (0.4-7.5 [4])3.5 (1.1-47.0 [9])
    IgA79.3 (54.4-80.1 [4])42.5a (27.0-348.7 [9])
  • a P < 0.05 compared with results for uninfected controls (as determined by the Kolmogorov-Smirnov test).