TABLE 1.

Deduced protein sequence identity and similarity of IroNE. coli and its putative plug domain to the Fe transport proteins IroNSal, FepA, IreA, FecA, and FhuA

OrganismHomologueComplete proteinPlug domaina
% Identityb (ratio)% Similarityb (ratio)% Identity (ratio)P valuec% Similarity (ratio)P valued
Salmonella entericaIroNSal82 (593/725)91 (661/725)92 (130/142)0.00198 (139/142)0.003
E. coliFepA52 (375/725)68 (492/725)71 (101/142)<0.00182 (116/142)<0.001
E. coliIreA27 (197/725)43 (312/725)45 (64/142)<0.00162 (88/142)<0.001
E. coliFecA21 (152/725)39 (282/725)16 (23/142)>0.1030 (43/142)0.06
E. coliFhuA18 (127/725)35 (251/725)18 (25/142)>0.1037 (52/142)>0.10
  • a As defined by the crystallographic structure for FepA (3), FecA (7), and FhuA (13) (see text).

  • b Determined by CLUSTAL alignments.

  • c Compared to the percent identity of the complete protein from the same strain (Fisher's exact test).

  • d Compared to the percent similarity of the complete protein from the same strain (Fisher's exact test).