TABLE 2.

Virulence of CP9 (wild type) and CP82 in a mouse urinary tract infection modellegend

Specimen and infecting strainMedian CFU/g or CFU/mlaNo. of samples (%) for which concn of strain exceeded that of the other:
>1-fold>3-fold≥10-fold
Bladder (n = 48)
    CP91.3 × 10441 (85)22 (46)6 (13)
    CP824.0 × 103b7 (15)f3 (6)f1 (2)h
Urine (n = 44)c
    CP92.0 × 10432 (73)23 (52)17 (39)
    CP826.1 × 10311 (25)f6 (14)f4 (9)f
Kidney (n = 48)
    CP95.3 × 10125 (52)20 (42)17 (35)
    CP822.8 × 101e10 (21)g7 (15)g6 (13)i
  • a Data were corrected for input ratios prior to statistical analysis.

  • b P = 0.0001 (Wilcoxon rank sum test).

  • c Urine specimens could not be obtained from four animals.

  • legend dP = 0.0004 (Wilcoxon rank sum test).

  • e P = 0.109 (Wilcoxon rank sum test).

  • f P < 0.01 (McNemar's test).

  • g P < 0.02 (McNemar's test).

  • h Not significant (McNemar's test).

  • i P < 0.05 (McNemar's test).