TABLE 1.

GAS strains used in this study

MGAS no.aemm typeSource/yr of isolationbDisease or characteristiccPresence of speL/speMd
30018Washington/1986-1990Invasive+/+
615718Texas/1998Invasive+/+
873818Texas/2000Invasive+/+
762918Illinois/1998Invasive+/+
15618Nebraska/1980sTSLS+/+
128618New York/unknownARF associated, LC 4RP104+/+
158218Ohio/1987ARF-associated+/+
158318Colorado/1968Nonhemolytic RF+/+
158518Illinois/1940sRF+/+
185618United Kingdom/1931RF; NCTC 8320+/+
823018Utah/1987ARF associated+/+
823218Utah/1987ARF+/+
755118Utah/1985Pharyngeal+/+
765518Utah/1985Pharyngeal+/+
767118Utah/1985Pharyngeal+/+
768718Utah/1985Pharyngeal+/+
803918Utah/1998-1999Pharyngeal+/+
805618Utah/1998-1999Pharyngeal+/+
770518Utah/1985Pharyngeal+/+
807718Utah/1998-1999Pharyngeal+/+
810018Utah/1998-1999Pharyngeal+/+
811818Utah/1998-1999Pharyngeal+/+
813818Utah/1998-1999Pharyngeal+/+
66618New York/1963Nasopharyngeal+/+
66718New York/1948Nasopharyngeal+/+
66818New York/1949Nasopharyngeal+/+
66918New York/1952Nasopharyngeal+/+
757418Illinois/1998Pharyngeal+/+
761218Illinois/1998Pharyngeal+/+
906018Illinois/1998Pharyngeal+/+
825318Lackland AFB/1999Pharyngeal+/+
831418Lackland AFB/1999Pharyngeal+/+
6505e18Lackland AFB/1993Carrier-Pharyngeal+/+
86101Utah/1998-1999Pharyngeal−/−
85742Utah/1998-1999Pharyngeal−/−
86253Utah/1998-1999Pharyngeal−/−
86124Utah/1998-1999Pharyngeal−/−
84885Utah/1998-1999Pharyngeal−/−
86746Utah/1998-1999Pharyngeal−/−
860211Utah/1998-1999Pharyngeal−/−
869712Utah/1998-1999Pharyngeal−/−
857722Utah/1998-1999Pharyngeal−/−
849428Utah/1998-1999Pharyngeal−/−
855749Utah/1998-1999Pharyngeal−/−
848677Utah/1998-1999Pharyngeal−/−
865689Utah/1998-1999Pharyngeal−/−
  • a Musser laboratory GAS strain number.

  • b Strains from Utah were collected during ARF outbreaks.

  • c Clinical diagnosis is provided when known. LC, Lancefield collection; RF, rheumatic fever; NCTC, National Collection of Type Cultures; TSLS, toxic shock-like syndrome.

  • d PCR was used to detect speL and speM. The genes were subsequently sequenced.

  • e Strain MGAS 6505 was obtained from an asymptomatic recruit enrolled in a study of GAS carriage at Lackland Air Force Base, San Antonio, Tex.