TABLE 1.

Correlation between production of CPB, CPA, and PFO in vitro and lethality in the i.g. and i.d. mouse models using whole cultures of C. perfringens type C

StrainaToxin typeLethality (%)In vitro toxin productionb
i.d.i.g.CPB (μg/ml)CPA (U/ml, 103)PFO (log2 titer)
CN1797C927518.95.53.9
CN2109C1008312.89.23.1
CN3685C100931362.9
CN3686C92061.21.9
CN3717C836710.52
CN3758C42014.85.2<1
CN3955C1005030.99.33.6
CN5383C100023.53.61.6
CN5388C58030.91.8
CN685C10008.91.12.2
CN885C1005823.66.32.6
CN886C1009224.15.14.2
JGS1071C5802.50.93.1
NCTC 10719C7502.70.7<1
ATCC 3624A000.81.7
Sterile TGY00
  • a Each mouse received approximately 3 × 108 CFU.

  • b Determined for a previous study (2).