TABLE 2.

GMCs (μg/ml) of anti-pneumococcal antibodies against the seven conjugate vaccine pneumococcal serotypes

Pneumococcal serotypeGMC (μg/ml [95% CI])
COPD patientsHealthy adultsHealthy adults after conjugate vaccination
45.04 (3.93-6.15)1.65a (0.48-2.81)19.95b (5.99-33.92)
6B55.76 (40.83-70.70)21.9 (7.02-36.84)76.70 (46.87-106.53)
9V16.38 (12.22-20.54)3.39a (0.85-5.95)13.41 (8.51-18.31)
147.06 (5.11-9.01)3.37 (0.28-6.47)30.74b (14.22-47.26)
18C17.49 (12.59-22.40)9.37 (3.80-22.54)56.53b (27.23-85.83)
19F36.34 (26.29-46.40)18.40 (4.97-31.82)66.76 (34.61-98.90)
23F18.08 (13.13-23.04)4.08 (0.64-7.50)55.43b (17.65-93.21)
  • a Significantly lower antibody level compared to patient group.

  • b Significantly higher antibody level compared to patient group.