TABLE 7.

Serovar Typhimurium strain SL1344 mutants lacking SPI-1 effector proteins: invasion of primary embryonic murine fibroblastsa

StrainRelevant genotypeInvasiveness (%)bNo. of assaysP vs:
TTSSEffectorsM556M557
SL1344Wild typeWild type82.17NS0.006
SB161invGWild type0.7170.001NS
M556sseDWild type10070.006
M557sseD invGWild type0.7440.006
M704sseDsopB60.07NS0.006
M719sseDsopEE271.47NS0.006
M716sseDsopBEE25.570.0010.006
M722sseDsopEE2 sipA42.970.0170.006
M707sseDsopBE sipA12.540.0060.029
M717sseDsopBE2 sipA55.74NS0.029
M708sseDsopBEE2 sipA2.560.0010.042
  • a The data were analyzed by using the Mann-Whitney U test (see Materials and Methods). NS, not significant (P ≥ 0.05).

  • b The invasiveness of M556 was defined as 100% (see Materials and Methods).