TABLE 2.

Cytokine and chemokine concentrations in the lung during S. pneumoniae pneumonia

Cytokine or chemokineResults (ng/g of lung) at indicated time (h) postinfectiona
2448
TLR4 mutantWTTLR4 mutantWT
TNF4.8 ± 0.83.1 ± 0.38.1 ± 2.64.6 ± 2.1
IL-69.6 ± 5.19.7 ± 4.666.7 ± 27.140.1 ± 29.9
KC35.8 ± 1.132.3 ± 0.7110.6 ± 33.571.2 ± 30.8
MIP-25.1 ± 1.76.2 ± 1.720.5 ± 7.110.0 ± 5.4
  • a Data represent means ± SEM for eight mice per group.