TABLE 3.

Lung and blood bacterial burden 24 h following inoculation with K. pneumoniae strains

Specimen sourceMedian (range) CFU by straina
Wild typeO-antigen-deficient mutant
Isometric doseIsolethal dose
Lung (entire organ)3 × 104 (9 × 102-1 × 105)5 × 104 (1 × 104-1 × 105)1 × 105 (3 × 103-4 × 105)
Blood (100 μl)9 × 101 (1 × 101-3 × 102)None detected1 × 101 (1 × 100-5 × 101)
  • a n = 5 for each group.