TABLE 1.

Demographics, inoculation conditions, and postinoculation results for enrolled women without a history of VVC

PreinoculationInoculationPostinoculation
RaceaAge (yr)BVbStage of MCcInoculum (theoretical/actual)VehicledKOHYeast swab cultureStatuseSymptomsfCell infiltrateg
AA38+Follicular1 × 104/1 × 104PBS++I3.9+
C29Follicular1 × 103/5 × 102PBS+C0
C47Luteal1 × 103/6 × 102PBS+C0
AA43+Follicular1 × 103/4 × 103PBSNC0
AA44+Luteal1 × 104/4 × 103PBSNC0
C36Follicular1 × 104/1 × 104PBSNC3.5
C44Follicular1 × 103/5 × 103PBSNC2.0
AA34+Follicular1 × 104/2 × 104PBSNC0
AA37+Luteal1 × 103/1 × 103PPdNC0
AA21+Follicular1 × 104/9 × 103PPw/glu+C0
AA44+Follicular1 × 106/1 × 106PBSNC2.0
C37Luteal1 × 107/1 × 107PBS++I6.6+
C47Luteal1 × 107/5 × 107PBS+C0
C43Follicular1 × 103/2 × 103PBS hyphal+C0
AA43+Follicular1 × 107/5 × 107PP+C0
C35±Follicular1 × 107/2 × 107PPw/gluNC0
AA33±Follicular1 × 107/1 × 107PPw/glu + est++C1
C29Follicular1 × 107/9 × 106PPw/glu+C0
AA46Follicular1 × 107/1 × 107PPw/glu++I2+
  • a AA, African American; C, Caucasian.

  • b +, positive; −, negative; ±, intermediate.

  • c MC, menstrual cycle.

  • d PPw/glu, PP-0.1% glucose; PPw/glu + est, PP-0.1% glucose-1% estrogen.

  • e I, infected; C, colonized; NC, not colonized.

  • f Severity of symptoms out of a possible of 12; 1 to 3, mild; 4 to 8, moderate; 9 to 12, severe.

  • g Presence of a cellular infiltrate postinoculation.