TABLE 3.

Comparison of antibody isotypes in responders to RAMA-D among individuals susceptible to and protected against P. falciparum infection during the course of the study

Antibody isotypePrevalenceaAntibody levelb
Protected (n = 28)Susceptible (n = 42)PcProtected (n = 28)Susceptible (n = 42)Pd
IgG167.8678.570.40470.155 (0.050, 0.605)0.295 (0.105, 0.580)0.544
IgG239.2930.950.60800.020 (0.005, 0.035)0.020 (0.010, 0.045)0.866
IgG385.7183.331.00000.060 (0.025, 0.130)0.085 (0.025, 0.205)0.560
IgG414.2938.100.03490.000 (0.000, 0.000)0.010 (0.000, 0.020)0.013
IgM78.5769.050.42410.100 (0.055, 0.480)0.165 (0.025, 0.330)0.871
  • a Percentage of positive sera defined as those that gave OD values greater than the cutoff OD.

  • b Antibody levels are presented as median OD values (lower quartile, upper quartile).

  • c Antibody prevalences of protected and susceptible groups were compared using Fisher's exact test.

  • d Antibody levels of protected and susceptible groups were compared using the Mann-Whitney test.