TABLE 5.

Reactivities of M. leprae CFP-10-specific T-cell hybridomas to M. leprae CFP-10 and M. leprae and M. tuberculosis peptides p1 and p2

T-cell hybridomaReactivity
M. leprae CFP-10M. leprae p1M. leprae p2M. tuber- culosis p1M. tuber- culosis p2
1G4+a++++
6G7++++++
5D4+++
8D11++++
  • a +++, optical density, >4.00; ++, optical density, 1.00 to 3.99; +, optical density, 0.20 to 0.99; −, background reading (optical density, <0.20; corresponds to <1 pg of IL-2 per ml). An optical density of >1.00 indicates production of >20 pg of IL-2 per ml by T-cell hybridomas.