TABLE 1.

Phenotypic characteristics of clinical isolates

IsolateLaccase activity (U/107 cells)bDoubling time (h)Capsule thickness (μm)bMIC (μg/ml) of drug for isolateaCapsule structure
ITZFCZAmBFluorescence intensity (MdF)Heterogeneity of the cell population (CVF)
C22199 ± 364.40.22 ± 0.071411.5244
C24173 ± 94.30.23 ± 0.080.25211.8238
C28178 ± 24.00.18 ± 0.070.2520.52.1233
C44181 ± 93.80.20 ± 0.070.540.51.9224
C45224 ± 333.60.16 ± 0.080.540.52.3250
C46188 ± 293.90.17 ± 0.070.5412.5231
C47182 ± 213.70.20 ± 0.060.540.54.6236
  • a ITZ, itraconazole; FCZ, fluconazole; AmB, amphotericin B.

  • b Data are means ± SD.