TABLE 5.

Comparative expression of B. pseudomallei strain SZ5028 genes in response to growth in M9 media containing 1.0% l-arabinose or d-glucose from analysis of whole-genome microarrays

Mean log2(IAra/IGlu)dGeneCommon nameOther name
3.660567716BPSL2188Isocitrate lyase
2.872528528BPSS1799Conserved hypothetical protein
2.396046588BPSL0638Putative membrane protein
2.30341532BPSS1802Putative membrane protein
2.214457543BPSL0688Putative glycerol-3-phosphate dehydrogenase
2.166956925BPSS0772MarR family regulatory protein
2.134310112BPSL0687Putative glycerol kinase
1.892752921BPSS1801Hypothetical transposon protein
1.876541084BPSS1800Putative dehydrogenase
1.82906867BPSS1575α-Ketoglutarate-dependent taurine dioxygenase
1.709388586BPSS1485bConserved hypothetical protein
1.704217668BPSS0310Hypothetical protein
1.604675546BPSL3396ATP synthase beta chain
1.492801878BPSS0190Putative O-acetylhomoserine phosphate transport system, substrate binding exported
1.491778582BPSL1359Periplasmic protein
1.485378831BPSS0153Glutamate-aspartate periplasmic binding protein
1.479761295BPSS1571Probable NADH oxidoreductase
1.447509585BPSS1553aPutative membrane protein
1.41337407BPSS1415Putative dehydrogenase-oxidoreductase protein
1.334014629BPSS1417Putative l-fuculose phosphate aldolase
1.284925131BPSS0973Mg2+ transport ATPase, P-type 2
1.277778343BPSL2336Putative glutamine synthetase
1.274610271BPSS0031Putative anaerobic growth regulatory protein
1.256584401BPSS0257Putative ribose ABC transport system, substrate binding exported protein
1.255907584BPSL3401ATP synthase c chain
1.177272863BPSL2500Electron transfer flavoprotein beta-subunit
1.157434208BPSS0260Putative kinase
1.131859522BPSS0885 N-Acylhomoserine lactone synthesis protein
1.084088768BPSS1572Permease component of taurine ABC transporter
1.072310657BPSL1363Phosphate transport system-related protein
1.065265887BPSL1362Phosphate transport system ATP-binding protein
1.053551864BPSS0519Conserved hypothetical protein
1.051120355BPSS0524Conserved hypothetical protein
1.049706097BPSS0771Hypothetical protein
1.038876362BPSS0977Putative cytochrome c subunit II
1.012236689BPSS0316Putative ACB transport system, membrane protein
0.993355473BPSL2611Maltose-binding protein
0.975444214BPSL2925Glutamate dehydrogenase
0.973999816BPSL1489Putative membrane protein
0.947238343BPSL2068Putative two-component system, response regulator
0.939612293BPSS0259Putative dehydrogenase
0.928566139BPSS0329Putative fatty aldehyde dehydrogenase
0.909462198BPSS0528Conserved hypothetical protein
0.905799795BPSS1638Putative hydratase
0.898099586BPSL3104Conserved hypothetical protein
0.888963775BPSL3399ATP synthase delta chain
0.88606119BPSS0034Putative fatty aldehyde dehydrogenase
0.875598331BPSL2970KDPG/KHG aldolase, putative
0.86945211BPSL2972Transcriptional regulator, IclR family
0.83562524BPSL2967 l-arabinose ABC transporter, ATP-binding protein
0.810672159BPSL1364Phosphate regulon two-component system response regulator
0.80527425BPSL3416Putative branched-chain amino acid ABC transporter, periplasmic substrate binding protein
0.799179699BPSS0156Putative dehydrogenase
0.794669183BPSL1961Putative electron transport protein
0.777504798BPSS0265Putative porin-related exported protein
0.755403028BPSS1356Hypothetical protein
0.750869748BPSS0526Hypothetical protein
0.747026223BPSS0154 d-Amino acid dehydrogenase small subunit
0.743456855BPSL2028Putative fimbriae assembly chaperone
0.73331917BPSL2177Hypothetical protein
0.711866447BPSL3021Cell division protein FtsA
0.695228684BPSL2024Putative two-component regulatory system, response regulator
0.668360942BPSS0308Putative aminotransferase
0.655842301BPSS16374-Hydroxybutyrate coenzyme A transferase
0.637379273BPSS0262Putative aminoglycoside 6′-N-acetyltransferase
0.628790939BPSS0303Putative diaminopimelate decarboxylase
0.625501197BPSS0307Putative aldehyde dehydrogenase
0.596306364BPSL2309Respiratory nitrate reductase alpha chain
0.590151581BPSL2066Putative exported protein
0.587354108BPSL0373Putative isocitrate dehydrogenase
0.583575109BPSL2189Conserved hypothetical protein
0.561185706BPSL1361Phosphate transport system permease protein
0.535335317BPSS1428Hypothetical protein
0.528600905BPSS0799Hypothetical protein
0.502223307BPSL0415Zinc-binding dehydrogenase (partial)
0.48860634BPSL1029Putative exported outer membrane porin protein
0.451071772BPSL1345Putative exported transglycosylase protein
0.447920038BPSS1911Putative membrane protein
0.43439967BPSL1876Putative phospholipase
0.415997942BPSS0945Putative lipoprotein
0.414734465BPSS0880Putative transcription elongation factor
0.39974228BPSL2315Endonuclease/exonuclease/phosphatase family
0.392807392BPSL1278Putative ABC transport system, iron-binding exported protein
0.386719733BPSL2027Putative fimbriae-related protein
0.37758332BPSS0974Subtilase family protease
0.376154287BPSL0812TetR family regulatory protein
0.372701224BPSL2840Putative flavohemoglobin like protein
0.369640959BPSS0944LysR family regulatory protein
0.350896899BPSL1904Putative exported protein
−0.265546681BPSL2397Hypothetical protein
−0.375599667BPSL1062Translation initiation factor IF-1
−0.385629165BPSS0648AraC family regulatory protein
−0.401476867BPSS2146Putative LysR family transcriptional regulator
−0.410106054BPSL2368Putative membrane protein
−0.418904592BPSL0600Hypothetical protein
−0.42521041BPSL0474Putative transporter protein
−0.461122926BPSS1508bHypothetical protein
−0.470627995BPSL3368Putative AraC family transcriptional regulator
−0.477031398BPSL0491Putative acyl carrier protein
−0.489581077BPSL2946C4-dicarboxylate transport protein
−0.500094955BPSS1867Putative membrane protein
−0.508615787BPSL1762Precorrin-3b C17-methyltransferase
−0.534798524BPSS1510bPutative membrane protein
−0.540333178BPSL1442Putative membrane protein
−0.551488165BPSS1004Putative acyl transferase
−0.578510311BPSS1240Putative penicillin-binding protein
−0.591347751BPSL1191Putative exported protein
−0.60912439BPSL0296Conserved hypothetical protein
−0.623616771BPSS1754Putative membrane protein
−0.62533172BPSS1535aSurface presentation of antigens proteinbsaY
−0.626547891BPSL1174Two-component system, sensor kinase protein
−0.634381721BPSL1170Putative membrane protein
−0.659601302BPSS1614cPutative type III secretion proteinbpscD2
−0.661862496BPSS0227Putative membrane protein
−0.666184002BPSS1744Putative cytochrome b561
−0.666845101BPSS1620cPutative type III secretion proteinbpscV2
−0.673719979BPSL2399Putative glycosyltransferase
−0.679727251BPSS1811cConserved hypothetical proteinhrpV (TTSS2)
−0.682518126BPSL2034Putative hydrolase
−0.684480069BPSL2540Putative inner membrane protein
−0.688717244BPSL2213Conserved hypothetical protein (pseudogene)
−0.692369046BPSS0008Putative TetR family regulatory protein
−0.693886932BPSS1489bPutative exported protein
−0.730982339BPSS1509bConserved hypothetical protein
−0.7331972BPSL2322Putative membrane protein
−0.744510147BPSS1501bConserved hypothetical protein
−0.766096437BPSL3310Flagellar regulon master regulator subunit FlhC
−0.770676455BPSS1504bPutative exported protein
−0.772200497BPSL1173Potassium-transporting ATPase c chain
−0.775876851BPSL2657Urease gamma subunit
−0.783460065BPSS2091Hypothetical protein
−0.796888021BPSS1117Conserved hypothetical protein
−0.810417894BPSS1613cPutative type III secretion proteinbpscE2
−0.826702179BPSL0192NADP-dependent alcohol dehydrogenase
−0.828794009BPSS1728Putative hemolysin activator
−0.852588312BPSS0692Fumarylacetoacetate hydrolase family
−0.856506201BPSL1591Conserved hypothetical protein
−0.881132891BPSS1118Putative HlyD family protein
−0.888650117BPSL1185Putative membrane protein
−0.925094352BPSL2111Putative LysR-family transcriptional regulator
−0.937413375BPSL2035Putative regulatory protein
−0.960146058BPSS1496bConserved hypothetical protein
−0.984330728BPSS1550aTTSS proteinbsaJ
−0.986561024BPSS1507bHypothetical protein
−0.996980632BPSS0966Putative manganese transport protein
−1.003770427BPSS1500bConserved hypothetical protein
−1.004140376BPSS1497bConserved hypothetical protein
−1.006872551BPSS1896Ubiquinol oxidase polypeptide I
−1.022502983BPSS1551aTTSS proteinsctKBp3
−1.023479736BPSS1782Organic hydroperoxide resistance protein
−1.035169118BPSL1322Putative heat shock protein
−1.036142443BPSL2301Pyruvate dehydrogenase E1 component
−1.038757904BPSL3369Acetaldehyde dehydrogenase
−1.045056203BPSL0494LysR family regulatory protein
−1.056941766BPSL2929Thermoresistant gluconokinase
−1.071013189BPSS1612cHypothetical proteinbpscF2
−1.125942579BPSL248950S ribosomal protein L19
−1.12671761BPSS0752Putative lipoprotein
−1.135350706BPSS2051Putative DNA-binding protein
−1.164923297BPSL1172Potassium-transporting ATPase b chain
−1.171472171BPSS1515bPutative transposase (partial)
−1.206749612BPSL1323Putative heat shock protein
−1.242957236BPSS1119Putative RND efflux transporter
−1.258189419BPSL2323Putative exported protein
−1.296885852BPSL3427Putative two-component sensor kinase
−1.357746981BPSS1363Putative exported protein
−1.36533721BPSS0910Conserved hypothetical protein
−1.42123191BPSS1534aSurface presentation of antigens proteinbsaZ
−1.467766735BPSL1171Potassium-transporting ATPase a chain
−1.467876647BPSL0024LrgA family protein
−1.507840263BPSS1491bConserved hypothetical protein
−1.558631442BPSS1503bHypothetical protein
−1.638155545BPSS1514bGTP cyclohydrolase I
−1.653768643BPSS0289Putative exported protein
−1.670203034BPSS1917Putative crp-family transcriptional regulator
−1.702728184BPSS0965Putative oxalate decarboxylase
−1.704025718BPSS1536aSurface presentation of antigens proteinbsaX
−1.725537375BPSS1748Hypothetical protein
−1.730257516BPSS1783Hypothetical protein
−1.756482379BPSL0025Putative membrane protein
−1.818503841BPSS1513bHypothetical protein
−1.820198806BPSS1532dPutative cell invasion proteinbapB
−1.842067577BPSS1541aSurface presentation of antigens proteinbsaS
−1.917238884BPSS1519bTransposase
−2.04912008BPSS0514Acetyl coenzyme A hydrolase/transferase
−2.08878765BPSS1520aPutative AraC-family transcriptional regulatorbprC
−2.136822097BPSS1498bConserved hypothetical protein
−2.147227432BPSS1537aSurface presentation of antigens proteinbsaW
−2.147273814BPSS0756Putative exported protein
−2.209090551BPSS1543aTTSS proteinbsaQ
−2.412295713BPSS1549dTTSS proteinbsaK
−2.447592658BPSS0753Hypothetical protein
−2.500150544BPSS1542aSurface presentation of antigens proteinbsaR
−2.772712922BPSS1526aPutative invasion proteinbapC
−2.80293907BPSS1523aPutative chaperonebicP
−2.868102303BPSS1545aTTSS proteinbsaO
−2.87670536BPSS1493aHypothetical protein
−2.928005448BPSS0755LysR family regulatory protein
−2.99669704BPSS1547aTTSS proteinbsaM
−3.023822001BPSS1494bPutative two-component response regulator
−3.166688057BPSS1548aTTSS proteinbsaL
−3.220777282BPSS1525aPutative G-nucleotide exchange factorbopE
−3.2758023BPSS1522aPutative two-component response regulatorbprB
−3.330120749BPSS1546aPutative AraC-family regulator of type III secretion systembsaN
−3.42729804BPSS1524aPutative intercellular spread proteinbopA
−4.034898051BPSS1521aHypothetical protein
−4.307254378BPSS1530aPutative HNS-like regulatory proteinbprA
−4.349596738BPSS1529aPutative membrane antigenbipD
−4.43240846BPSS1533aSurface presentation of antigens proteinbicA
−5.391462205BPSS1516bHypothetical protein
−5.818423748BPSS1517bHypothetical protein
  • a TTSS3 gene.

  • b Putative TTSS3 additional gene.

  • c TTSS gene.

  • d Mean log2(IAra/IGlu) = average value of the log2-based ratio of intensities from two channels of the microarray: growth in arabinose versus growth in glucose.