TABLE 3.

The fifty most abundant transcripts detected in uninfected jejunal epithelium

ProbeaGenBank no.NameCell type (fold change)b
92812_f_atM33225Cryptdin-1P
96094_atU79575Apolipoprotein A-I
AFFXActinMur/M12481_3_atV00478Actin cytoplasmic 1
100351_f_atU02997Cryptdin-2P
99551_f_atU12560Cryptdin-5P
100078_atM13966Apolipoprotein A-IV
95766_f_atU03066Cryptdin-16P
93863_f_atU12561Cryptdin-6/12P
100213_f_atU9386260S ribosomal protein L41
93879_f_atU12559Cryptdin-3P
101255_atX51703Ubiquitin
96009_s_atD13509Pancreatitis-associated protein 1
100106_atD38410Intestinal trefoil factorG
99926_atAB001489Polyimmunoglobulin receptorE
AFFX-GapdhMur/M32599_3_atM32599Glyceraldehyde-3-phosphate dehydrogenase
160221_atAA709879RIKEN cDNA 2200008F12 gene (similar to Q9CQW5 [mouse galectin-2])
160145_atAI593999RIKEN cDNA 1810010M01 gene
98092_atAA790307Onzin
94061_atM13018Cysteine-rich protein 1
101794_f_atU12562Cryptdin 1P
94805_f_atM33988Histone H2A.1
92735_atX74266Phospholipase A2 (membrane associated)P
95621_atAA606367RIKEN cDNA 9030623C06 gene
102755_atAB016496Intelectin-1P
160099_atAF026799Galectin-6
94766_atM22432Elongation factor 1-alpha 1
97887_atZ15090Apolipoprotein C-II
99993_atU77083Aminopeptidase N(−2.8)
97889_atM65034Fatty acid-binding protein (intestinal)E
101009_atX12789Keratin type II (cytoskeletal 8)
99631_f_atL06465Cytochrome c oxidase polypeptide VIa-liver (mitochondrial)
99660_f_atX52940Cytochrome c oxidase polypeptide VIIc (mitochondrial)
96573_atX13055Actin cytoplasmic 2
101213_atX1526760S acidic ribosomal protein P0
95569_atU95182UroguanylinE
98000_atJ04634Cell surface antigen 114/A10 (lymphocyte antigen 64)(−2.4)
101886_f_atAJ413953ARF-related protein 1
94738_s_atM33227Cryptdin-related protein 4C-1P (−6.5)
102364_atJ04509Transcription factor jun-D
97826_atAI465965Clone IMAGE:4988271 similar to human IgG Fc binding protein [BAA19526]
102599_atX06407Translationally controlled tumor protein
94075_atY14660Fatty acid-binding protein (liver)
95072_atAK002815Cytochrome c-1
94492_atAB025406Destrin (actin-depolymerizing factor)
94767_atU9386440S ribosomal protein S11
101753_s_atX51547Lysozyme C type PP
97540_f_atM69069Histocompatibility 2 (D region locus 1)
160611_atAK004724Family 4 cytochrome P450
93798_atAI839988Similar to ATPase (Na+K+ transporting) alpha 1 polypeptide
93120_f_atJ00400H-2 class I histocompatibility antigen (K-B alpha chain)
  • a Affymetrix probe set identification numbers are shown, ranked in decreasing order of abundance in uninfected epithelium.

  • b The cell specificity, where known: P, Paneth cell; G, goblet cell; E, enterocyte. When any transcript was found to change significantly (P ≤ 0.001 [t test with Welch correction; n = 4]) on infection, the fold change is noted in parentheses).