TABLE 1.

RpoSBb is required for virulence in B. burgdorferi

StrainDescriptionVirulence in:Reference or source
C3H/HeJaSCIDbDMCc
297Uncloned wild type9/9NDY77
AH200297 rpoS::ermr0/9NDY47
CE162Wild-type 297 clone10/108/8YThis work
CE174162 rpoS::ermr0/100/8YThis work
CE467CE164 + rpoS/pCE3205/57/8NDThis work
  • a Infectivity determined by immunoblot assay and cultivation of tissue biopsies.

  • b Infectivity determined by cultivation of tissue biopsies. ND, not determined.

  • c Survival of spirochetes within DMCs assessed by enumeration following explantation. ND, not determined.