TABLE 2.

Percentage uptake of C. albicans cell wall and hypha-deficient mutants by macrophages

Ratio% Uptake of C. albicans mutant by macrophagesa
CAI4ece1Δals3Δals3Δ::ALS3hwp1Δhwp1Δ::HWP1
3:155.0 ± 4.860.7 ± 653.3 ± 1.252.3 ± 8.651 ± 10.859 ± 14.2
NGY152CAI4clb2Δhgc1Δefg1Δcph1Δefg1Δ cph1Δ
1:129.3 ± 3.531.3 ± 8.121.7 ± 3.835.3 ± 5.126.3 ± 0.632.7 ± 9.3
3:143.3 ± 4.550.3 ± 3.543.7 ± 2.542.3 ± 4.246.3 ± 1.544 ± 5.3
  • a The values shown are means ± standard deviations from three separate triplicate experiments. Data are shown for the 3-h time point at 1:1 and 3:1 C. albicans/J774 macrophage ratios.