TABLE 1.

MGC formation in human in vitro granulomas exposed to M. tuberculosis (H37Rv), the isogenic mutant lacking the cpn60.1 gene, and the complemented strain

Duration of culture (days)Mean % MGC ± SDa
Wild typeΔcpn60.1 mutantΔcpn60.1 complemented mutant
3000
6000
930.3 ± 4.53.2 ± 1.628.7 ± 1.5
  • a Results are expressed as the means of three individual experiments.