TABLE 1.

Efficacy of invasion of the intestinal mucosae of C57BL/6 mice and B-cell-deficient mice (lacking Peyer's patches) by M. avium subsp. paratuberculosis using an intestinal-loop modela

Bacterium% of inoculum inside the mucosab
C57BL/6J miceB-cell-deficient mice
1 h3 h1 h3 h
M. avium subsp. paratuberculosis5.1 ± 0.336 ± 104.3 ± 0.530 ± 6
M. avium subsp. hominissuis7.6 ± 0.454 ± 96.8 ± 0.352 ± 4
  • a Bacteria (1.7 × 107 M. avium subsp. hominissuis organisms or 2.5 × 107 M. avium subsp. paratuberculosis organisms) were injected into the intestinal loop.

  • b The experiment was repeated twice, with a total of 10 mice per time point. P was >0.05 for comparison of the percentages of invasion of C57BL/6J versus B-cell-deficient mice.