TABLE 4.

Impact of the β1 integrin receptor on the entry of M. avium subsp. paratuberculosis into MDBK cells

Experimental groupS. aureusM. avium subsp. paratuberculosis
No. of intracellular bacteriaa% ΔbNo. of intracellular bacteriaa% Δ
Control (no antibody)(3.4 ± 0.5) × 104(2.6 ± 0.4) × 103
Anti-α5β1(5.1 ± 0.3) × 10385c(9.7 ± 0.2) × 10237.3d
Anti-LPS(3.2 ± 0.4) × 104−5d(3.0 ± 0.3) × 10315d
  • a The inoculum was 1.8 × 105 organisms for S. aureus and 1.1 × 105 organisms for M. avium subsp. paratuberculosis.

  • b Δ, reduction.

  • c P < 0.05 for comparison with the no-antibody control.

  • d P > 0.05 for comparison with the no-antibody control.