Table 2.

Efficacy of Salmonella Enteritidis FliC monomers or polymers in protecting CD-1 mice from lethal challenge with wild-type S. Enteritidis R11a

VaccineMortality (no. of dead mice/total no. of mice)P valuebVaccine efficacy (%)
Flagellin monomer0/20<0.0001100
Flagellar polymer0/20<0.0001100
  • a The mice were challenged with 5 × 105 CFU S. Enteritidis R11 intraperitoneally (IP). (LD50 of 2.2 × 105 CFU).

  • b The mortality rate of the vaccinated group compared to PBS-immunized control animals by two-tailed Fisher's exact test.