TABLE 1.

Significantly differentially expressed genes at each time pointa

Gene sorting methodNo. of genes
E. coli challengeS. aureus challenge
1 h3 h6 h24 hTotal1 h3 h6 h24 hTotal
Total significantly differentially expressedb
    All104382325306172733111
    Upregulated8228727223115272881
    Downregulated2295537520530
According to time to reach max altered mRNA concnc
    All61243157164625131410101138
    Concn increased421601301004321114871104
    Concn decreased198327641932023034
    Exceeding 10-fold regulation1425171369130711
  • a Considered are only genes with known IPA-eligible human orthologs.

  • b Total numbers of significantly differentially expressed genes at each time point.

  • c Number of genes sorted according to the time (p.i.) of reaching their maximally altered mRNA concentration.