TABLE 1

Bacterial loads in fluids and tissues in the sepsis model with A. baumannii strain ATCC 17978

Time and conditionaBacterial load (log10 CFU per g of tissue or per ml of fluid) in:Bacteremia (%)
SpleenLungsPFbBlood
4 h
    N3.98 ± 0.304.07 ± 0.534.06 ± 1.293.19 ± 0.42100
    H3.88 ± 0.234.07 ± 0.703.72 ± 1.153.18 ± 0.28100
Time of death
    N8.79 ± 0.569.36 ± 0.359.31 ± 0.338.40 ± 0.56100
    H8.32 ± 0.718.25 ± 0.54e8.88 ± 0.53c7.73 ± 0.20d100
    H (6 h) + N7.90 ± 0.30f8.32 ± 0.46f8.75 ± 0.33f7.85 ± 0.32100
  • a N, normoxia; H, hypoxia.

  • b PF, peritoneal fluid.

  • c P < 0.05 (H versus N at the time of death).

  • d P < 0.01 (H versus N at the time of death).

  • e P < 0.001 (H versus N at the time of death).

  • f P < 0.05 [H (6 h) + N versus N at the time of death].