TABLE 3

Activation of Vβ subfamilies in response to RF122-encoded SAgs

SAgBovine Vβ subfamily(ies) activatedaHuman Vβ subfamily(ies) activateda,b
SECbov15, 17, 2812, 13, 14, 15, 17, 20
SEIbov1, 10, 161, 5, 6, 23
SElLbov1, 5, 6, 7, 10, 16, 241, 5, 7, 16, 22, 23
SElNbov3, 9, 16, 24, X7, 8, 9, 17
SElXbov3, 5, 8, 11, 16, 17, 24, X1, 6, 18, 21
TSST-1bov2, 4, 24, X2
SEGbov3, 5, 13, 15, 17, X3, 12, 13, 14, 15
SElUbov1713, 14
SElYbov4, 7, 10, 16, 24, 28, X1, 2, 3, 5, 6, 7, 15, 21, 22, 23, 24
SElZbov1, 3, 7, 11, 16, 17, 24, 28, X13.2
SElObovNA5, 7
  • a Vβ subfamilies were named according to the classification described previously by Arden et al. (47). Bovine and human Vβ subfamilies activated in response to the same SAg are highlighted in boldface type. NA, not applicable.

  • b Human Vβ activation data were compiled previously or in this study for SElY and SElZ (11, 12, 14, 15).