Table 1.

Bacterial densities in infected vegetations and spleens of animals 24 h after challenge with Streptococcus spp. or S. aureus tested strainsa

StrainInoculum (CFU/ml)Median (range) log10 CFU/g in:
VegetationsSpleens
BolusContinuous infusionBolusContinuous infusion
S. intermedius1056.2 (3.5–7.7)5.1 (4.7–8.1)2.1 (1.7–2.5)2.5 (1.7–3.4)
1067.3 (7.1–7.6)6.3 (3.4–7.6)3.3 (3.0–3.6)2.6 (1.8–3.2)
S. gordonii1057.6 (4.0–8.1)6.2 (3.7–6.9)2.9 (2.2–3.6)3.1 (2.4–3.2)
1067.8 (6.2–8.2)6.4 (6.0–7.9)3.3 (2.6–4.6)3.0 (2.6–3.4)
MSSA Newman1038.5 (3.0–9.4)8.3 (5.4–9.3)2.5 (1.6–4.5)3.2 (1.8–4.6)
1049.4 (5.6–9.4)8.8 (5.8–9.4)3.9 (2.2–4.9)4.5 (1.9–4.8)
MRSA P81039.2 (4.6–9.4)7.1 (6.1–9.3)4.5 (1.7–4.9)3.9 (1.7–4.7)
1049.3 (5.2–9.6)8.6 (4.1–9.6)4.6 (2.6–4.8)4.5 (1.7–4.7)
  • a Differences between values were not statistically different(P > 0.05) as analyzed by the Mann-Whitney test.