Table 1

Increased expression of CD25, CD80, CD83, CCR7, and PDL-1 but reduced expression of CD209 by H. pylori-infected DCs

TreatmentaSurface molecule expression (median MFI)b
CD25CD40CD80CD83CD86CD209CCR7PDL-1HLA-DR
H. pylori26* (18, 27)303 (114, 525)48* (15, 53)15* (8, 79)160 (44, 222)15* (9, 65)7* (3, 20)92* (16, 250)114 (71, 187)
LPS1 (0, 15)340 (64, 502)42* (16, 65)18* (15, 61)216* (45, 320)28 (11, 133)5 (1, 6)88 (17, 93)143 (106, 271)
Medium0 (0, 0)309 (35, 433)8 (3, 23)8 (1, 13)179 (16, 261)35 (25, 169)1 (0, 3)26 (3, 34)56 (55, 290)
  • a H. pylori, infected with H. pylori; LPS, activated by LPS; medium, incubated in medium only.

  • b Values are based on seven independent experiments (seven donors). MFIs of isotype controls were subtracted. Values in parentheses are the 25th and 75th percentile MFIs, respectively.

  • * , P < 0.05 (Friedman test and Dunn's multiple comparison test).