Table 2

Increased expression of CD14 and CD32 but reduced expression of CD11b by H. pylori-infected M1 macrophages

TreatmentaSurface molecule expression (median MFI)b
CD11bCD14CD16CD32CD64CD80CD86CD206HLA-DR
H. pylori17* (9, 21)52* (26, 72)2 (1, 4)44* (38, 47)0 (0, 2)12 (1, 14)6 (4, 8)21 (0, 26)25 (21, 40)
LPS27 (13, 34)24 (18, 49)4 (2, 5)43 (37, 46)0 (0, 2)13* (3, 20)13 (9, 23)13 (0, 38)39 (30, 41)
Medium61 (11, 81)12 (8, 18)3 (1, 6)32 (28, 37)1 (0, 3)1 (0, 3)12 (8, 18)33 (0, 64)47 (43, 63)
  • a H. pylori, infected with H. pylori; LPS, stimulated with LPS; medium, treated with medium only.

  • b Values are based on at least six independent experiments (six donors). MFIs of isotype controls were subtracted. Values in parentheses are the 25th and 75th percentile MFIs, respectively.

  • * , P < 0.05 (Friedman test and Dunn's multiple comparison test).