Table 3

Increased expression of CD14, CD32, and CD206 by H. pylori-infected M2 macrophages

TreatmentaSurface molecule expression (median MFI)b
CD11bCD14CD16CD32CD64CD80CD86CD206HLA-DR
H. pylori2 (2, 33)108* (50, 241)10 (5, 13)95* (39, 125)0 (0, 2)0 (0, 2)0 (0, 2)27* (5, 30)17 (13, 24)
LPS2 (1, 27)59 (39, 216)7 (4, 14)47 (29, 84)0 (0, 5)0 (0, 4)0* (0, 1)5 (4, 9)16 (11, 22)
Medium2 (2, 45)43 (12, 110)5 (2, 9)50 (25, 73)0 (0, 5)0 (0, 2)2 (1, 5)4 (2, 10)22 (14, 58)
  • a H. pylori, infected with H. pylori; LPS, stimulated with LPS; medium, treated with medium only.

  • b Values are based on at least five independent experiments (five donors). MFIs of isotype controls were subtracted. Values in parentheses are the 25th and 75th percentile MFIs, respectively.

  • * , P < 0.05 (Friedman test and Dunn's multiple comparison test).