Table 3

Response to inoculation with live H. ducreyi

Volunteer (gender)aObservation period (days)StrainbDose (CFU)cNo. of initial papulesFinal outcome of papule
No. resolvedNo. of pustules
411 (M)6P14622
M39-15500
412 (M)8P146321
M39-155220
413 (F)8P14622
M39-15533
414 (F)7P113220
M47-187211
417 (F)8P13622
M104220
418 (M)6P13633
M104321
419 (M)7P13633
M10432
  • a Volunteer 411, 412, and 413 were inoculated in the first iteration; volunteer 414 in the second iteration; volunteers 417, 418, and 419 in the third iteration. M, male; F, female.

  • b P, parent strain 35000HP; M, mutant strain 35000HPΔcsrA.

  • c Doses inoculated at 3 sites, except 39-155, one dose each of 39, 78, and 155 CFU; 47-187, one dose each of 47, 94, and 187 CFU.