Table 1

Variant loci identified in Anaplasma marginale subsp. centrale (vaccine strain)

Locus no.Locus base rangeaNo. of genotypes foundbGene affectedcVariant type(s)d
125850–258942ACIS_00031 (virB2)S, I
2278122IntergenicS
6482582IntergenicS
752263–522752IntergenicP
863508–637164ACIS_00070 (msp3 psi 1)S
10168717–1687477IntergenicP
111916042ACIS_00221 (ribA)S
12203447–2037022ACIS_00229 (msp2)S, I
13231145–2311572ACIS_00257P
142619212ACIS_00286 (ana29)S
15285308–2853142ACIS_00307P
162861362ACIS_00307S
17297256–2972672IntergenicP
203328522ACIS_00354 (msp3 psi 4)S
21354767–3547782ACIS_00380P
22371736–3717552IntergenicP
23383967, 3844572ACIS_00406 (folP)S
24464122–4641342IntergenicP
254896732ACIS_00524S
26556700, 5567183ACIS_00590S
29615162–6151832ACIS_00637S, I
30664156–6641663ACIS_00680P
31665231–6652432ACIS_00680P
33667248–6682358ACIS_00684S, I
34716390, 716443–7164493IntergenicS, P
35787408–7874202IntergenicP
368127902ACIS_00828 (rluC)S
37857112–8571233ACIS_00875P
38858661–8586723ACIS_00877P
39886412–8864223ACIS_00900P
40896567–8965773IntergenicP
41914652–9146642IntergenicP
42918907–9189172ACIS_00933P
439280892ACIS_00940S
44936018–9360293IntergenicP
45936661–9384714ACIS_00943S, I
469472512ACIS_00946S
47965621–9656323ACIS_00966 (mutL)P
481091360, 10913932ACIS_01093S
491096096–10961074ACIS_01096P
501097405–109846211ACIS_1097 (msp1B-1)S, I
5111269312ACIS_1127S
521127137–11271412IntergenicS, I
531138500–11385202ACIS_01138S, I
541184195, 1184314–11843202ACIS_01181 (virB2)S
56498607–4991282ACIS_00530R
  • a Base range in Anaplasma marginale subsp. centrale (vaccine strain), RefSeq NC_013532.1. A single number reflects the presence of an SNP in the locus and thus no change in locus size.

  • b Minimum number of genotypes observed in the whole-genome shotgun (WGS) sequencing.

  • c ACIS refers to the locus tag prefix for RefSeq NC_013532.1.

  • d Abbreviations: S, single-nucleotide polymorphism; P, polynucleotide stretch; I, insertion/deletion (indel), R, perfect repeat.