TABLE 1

Histological analysis of H&E-stained lung sections 21 days after aerosol challenge

GenotypeMean histological scorea
NecrosisHemorrhageEdemaCryptococcusInflammationComposite
WT2.71.317.76.719.3
SP-D−/−31.70.33.7412.7
  • a Data are for 2 to 5 mice/group. Sham-infected WT and SP-D−/− mice received a score of 0 for each category.