TABLE 2

Sequence variation of MG 192 subvariable regions based on sequence analysis of 97 variant sequences from 29 M. genitalium clinical specimens

Subvariable regionLocation (aa)aLength of subvariable regionbFrequency of amino acid changec
V152–67160.0052
V283–10620–270.0095–0.0129
V3119–146280.0107
V4170–19221–230.0215–0.0236
V5202–217160.0064
V6237–26728–340.0131–0.0158
V7277–28711–120.0069–0.0075
V8328–33690.0080
V9363–37080.0052
V10409–4194–12 (polyserine)0.0112–0.0335
V11471–49727–290.0124–0.0130
  • a Relative to the predicted MG192 amino acid sequence of the type strain G37 (GenBank accession no. NC_000908). aa, amino acids.

  • b Number of amino acids.

  • c Calculated by dividing the number of unique sequences for each region by the total number of MG192 variants (97) and then by the number of amino acids in each region.