TABLE 4

NrdR-dependent expression of genes identified by transcriptomic analysis

GeneOperon arrangementLog fold changeaGene product
nrdHnrdHIEF2.29Glutaredoxin-like protein
nrdI2.32Ribonucleotide reductase stimulatory protein: flavodoxin
nrdE2.28Ribonucleotide-diphosphate reductase subunit alpha
nrdF1.92Ribonucleotide-diphosphate reductase subunit beta
dicBdicB ydfDE insD intQ1.15Cell division inhibition protein
ydfD1.44Hypothetical protein
yieIyieIJ1.13Putative inner membrane protein
ycgRycgR−1.08Flagellar function protein
fliDfliDST−1.21Flagellar filament capping protein
fliS−1.34Flagellar biosynthesis protein FliS
fliT−1.39Flagellar biosynthesis protein FliT
aeraer−1.47Aerotaxis receptor
fliCfliC−1.56Flagelline
motAmotAB cheAW−1.63Flagellar motor protein; proton conduct
motB−1.75Flagellar motor protein; motor rotation
cheA−1.82Chemotaxis protein; chemotactic sensory histidine kinase
cheW−2.06Purine-binding chemotaxis protein
tartar tap cheRBYZ−2.26Methyl-accepting chemotaxis protein II
tap−2.36Methyl-accepting chemotaxis protein IV
cheR−1.96Chemotaxis methyltransferase; regulator
cheB−2.01Chemotaxis-specific methylesterase; chemotaxis regulator
cheY−2.18Chemotaxis regulator transmitting signal
cheZ−2.01Chemotaxis protein phosphatase for CheY; chemotaxis regulator
tsrtsr−2.35Methyl-accepting chemotaxis protein I
yhjHyhjH−2.26EAL domain-containing protein
ymdAymdA−1.31Hypothetical protein
yjcZyjdAZ−1.88Hypothetical protein
yhjGyhjG−1.48Hypothetical protein
kdgKkdgK−2.792-Dehydro-3-deoxygluconokinase
  • a Log fold change was determined by comparing the transcription (ratio of mRNA) of Pseudomonas aeruginosa ΔnrdR to its wild-type strain PAO1 (ΔnrdR mRNA/wild-type mRNA).